Development by Genetic Immunization of Monovalent Antibodies Against Human Vasoactive Intestinal Peptide Receptor 1 (VPAC1), New Innovative, and Versatile Tools to Study VPAC1 Receptor Function

Multi-membrane spanning proteins, such as G protein-coupled receptors (GPCRs) and ion channels, are extremely difficult to purify as native proteins. Consequently, the generation of antibodies that recognize the native conformation can be challenging. By combining genetic immunization, phage display...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Peyrassol, Xavier, Laeremans, Toon, Lahura, Vannessa, Debulpaep, Maja, El Hassan, Hassan, Steyaert, Jan, Parmentier, Marc, Langer, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895782/
https://ncbi.nlm.nih.gov/pubmed/29674997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00153
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