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Nucleosomes of polyploid trophoblast giant cells mostly consist of histone variants and form a loose chromatin structure

Trophoblast giant cells (TGCs) are one of the cell types that form the placenta and play multiple essential roles in maintaining pregnancy in rodents. TGCs have large, polyploid nuclei resulting from endoreduplication. While previous studies have shown distinct gene expression profiles of TGCs, thei...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Hayakawa, Koji, Terada, Kanae, Takahashi, Tomohiro, Oana, Hidehiro, Washizu, Masao, Tanaka, Satoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895725/
https://ncbi.nlm.nih.gov/pubmed/29643413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23832-2
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