Utility-Weighted Modified Rankin Scale as Primary Outcome in Stroke Trials: A Simulation Study

BACKGROUND AND PURPOSE—: The utility-weighted modified Rankin Scale (UW-mRS) has been proposed as a new patient-centered primary outcome in stroke trials. We aimed to describe utility weights for the mRS health states and to evaluate the statistical efficiency of the UW-mRS to detect treatment effec...

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Publié dans:Stroke
Auteurs principaux: Dijkland, Simone A., Voormolen, Daphne C., Venema, Esmee, Roozenbeek, Bob, Polinder, Suzanne, Haagsma, Juanita A., Nieboer, Daan, Chalos, Vicky, Yoo, Albert J., Schreuders, Jennifer, van der Lugt, Aad, Majoie, Charles B.L.M., Roos, Yvo B.W.E.M., van Zwam, Wim H., van Oostenbrugge, Robert J., Steyerberg, Ewout W., Dippel, Diederik W.J., Lingsma, Hester F.
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2018
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Original Contributions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895119/
https://ncbi.nlm.nih.gov/pubmed/29535271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.117.020194
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