Utility-Weighted Modified Rankin Scale as Primary Outcome in Stroke Trials: A Simulation Study

BACKGROUND AND PURPOSE—: The utility-weighted modified Rankin Scale (UW-mRS) has been proposed as a new patient-centered primary outcome in stroke trials. We aimed to describe utility weights for the mRS health states and to evaluate the statistical efficiency of the UW-mRS to detect treatment effec...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Dijkland, Simone A., Voormolen, Daphne C., Venema, Esmee, Roozenbeek, Bob, Polinder, Suzanne, Haagsma, Juanita A., Nieboer, Daan, Chalos, Vicky, Yoo, Albert J., Schreuders, Jennifer, van der Lugt, Aad, Majoie, Charles B.L.M., Roos, Yvo B.W.E.M., van Zwam, Wim H., van Oostenbrugge, Robert J., Steyerberg, Ewout W., Dippel, Diederik W.J., Lingsma, Hester F.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
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Original Contributions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895119/
https://ncbi.nlm.nih.gov/pubmed/29535271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.117.020194
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