Utility-Weighted Modified Rankin Scale as Primary Outcome in Stroke Trials: A Simulation Study

BACKGROUND AND PURPOSE—: The utility-weighted modified Rankin Scale (UW-mRS) has been proposed as a new patient-centered primary outcome in stroke trials. We aimed to describe utility weights for the mRS health states and to evaluate the statistical efficiency of the UW-mRS to detect treatment effec...

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Vydáno v:Stroke
Hlavní autoři: Dijkland, Simone A., Voormolen, Daphne C., Venema, Esmee, Roozenbeek, Bob, Polinder, Suzanne, Haagsma, Juanita A., Nieboer, Daan, Chalos, Vicky, Yoo, Albert J., Schreuders, Jennifer, van der Lugt, Aad, Majoie, Charles B.L.M., Roos, Yvo B.W.E.M., van Zwam, Wim H., van Oostenbrugge, Robert J., Steyerberg, Ewout W., Dippel, Diederik W.J., Lingsma, Hester F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2018
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Original Contributions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895119/
https://ncbi.nlm.nih.gov/pubmed/29535271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.117.020194
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