DEC205-DC targeted DNA vaccine against CX3CR1 protects against atherogenesis in mice

Studies disrupting the chemokine pathway CX3CL1 (fractalkine)/ CX3CR1 have shown decreased atherosclerosis in animal models but the techniques used to interrupt the pathway have not been easily translatable into human trials. DNA vaccination potentially overcomes the translational difficulties. We e...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhou, Jimmy Jianheng, Wang, Yuan Min, Lee, Vincent W. S., Zhang, Geoff Yu, Medbury, Heather, Williams, Helen, Wang, Ya, Tan, Thian Kui, Harris, David C. H., Alexander, Stephen I., Durkan, Anne M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895033/
https://ncbi.nlm.nih.gov/pubmed/29641559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195657
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