Inhibition of galectin-3 ameliorates the consequences of cardiac lipotoxicity in a rat model of diet-induced obesity

Obesity is accompanied by metabolic alterations characterized by insulin resistance and cardiac lipotoxicity. Galectin-3 (Gal-3) induces cardiac inflammation and fibrosis in the context of obesity; however, its role in the metabolic consequences of obesity is not totally established. We have investi...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Marín-Royo, Gema, Gallardo, Isabel, Martínez-Martínez, Ernesto, Gutiérrez, Beatriz, Jurado-López, Raquel, López-Andrés, Natalia, Gutiérrez-Tenorio, Josué, Rial, Eduardo, Bartolomé, María Visitación, Nieto, María Luisa, Cachofeiro, Victoria
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894945/
https://ncbi.nlm.nih.gov/pubmed/29361517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.032086
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