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Nanomotor-Enabled pH-Responsive Intracellular Delivery of Caspase-3: Towards Rapid Cell Apoptosis

Direct and efficient intracellular delivery of enzymes to cytosol holds tremendous therapeutic potential while remaining an unmet technical challenge. Herein, an ultrasound (US)-propelled nanomotor approach and a high pH-responsive delivery strategy is reported to overcome such challenge using caspa...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: de Ávila, Berta Esteban-Fernández, Ramírez-Herrera, Doris E., Campuzano, Susana, Angsantikul, Pavimol, Zhang, Liangfang, Wang, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894870/
https://ncbi.nlm.nih.gov/pubmed/28467853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.7b01926
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