Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma

Gastroesophageal adenocarcinoma (GEA) is a lethal disease where targeted therapies, even when guided by genomic biomarkers, have had limited efficacy. A potential reason for the failure of such therapies is that genomic profiling results could commonly differ between the primary and metastatic tumor...

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Detaylı Bibliyografya
Yayımlandı:Cancer Discov
Asıl Yazarlar: Pectasides, Eirini, Stachler, Matthew D., Derks, Sarah, Liu, Yang, Maron, Steven, Islam, Mirazul, Alpert, Lindsay, Kwak, Heewon, Kindler, Hedy, Polite, Blase, Sharma, Manish R., Allen, Kenisha, O’Day, Emily, Lomnicki, Samantha, Maranto, Melissa, Kanteti, Rajani, Fitzpatrick, Carrie, Weber, Christopher, Setia, Namrata, Xiao, Shu-Yuan, Hart, John, Nagy, Rebecca J., Kim, Kyoung-Mee, Choi, Min-Gew, Min, Byung-Hoon, Nason, Katie S., O’Keefe, Lea, Watanabe, Masayuki, Baba, Hideo, Lanman, Rick, Agoston, Agoston T, Oh, David J., Dunford, Andrew, Thorner, Aaron R., Ducar, Matthew D., Wollison, Bruce M., Coleman, Haley A., Ji, Yuan, Posner, Mitchell C., Roggin, Kevin, Turaga, Kiran, Chang, Paul, Hogarth, Kyle, Siddiqui, Uzma, Gelrud, Andres, Ha, Gavin, Freeman, Samuel S., Rhoades, Justin, Reed, Sarah, Gydush, Greg, Rotem, Denisse, Davison, Jon, Imamura, Yu, Adalsteinsson, Viktor, Lee, Jeeyun, Bass, Adam J., Catenacci, Daniel V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894850/
https://ncbi.nlm.nih.gov/pubmed/28978556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-0395
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