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Are pilot trials useful for predicting randomisation and attrition rates in definitive studies: A review of publicly funded trials

BACKGROUND/AIMS: External pilot trials are recommended for testing the feasibility of main or confirmatory trials. However, there is little evidence that progress in external pilot trials actually predicts randomisation and attrition rates in the main trial. To assess the use of external pilot trial...

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Publicado en:Clin Trials
Main Authors: Cooper, Cindy L, Whitehead, Amy, Pottrill, Edward, Julious, Steven A, Walters, Stephen J
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894808/
https://ncbi.nlm.nih.gov/pubmed/29361833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774517752113
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