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Functional domains of SP110 that modulate its transcriptional regulatory function and cellular translocation

BACKGROUND: SP110, an interferon-induced nuclear protein, belongs to the SP100/SP140 protein family. Very recently, we showed that SP110b, an SP110 isoform, controls host innate immunity to Mycobacterium tuberculosis infection by regulating nuclear factor-κB (NF-κB) activity. However, it remains unc...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Leu, Jia-Shiun, Chang, So-Yi, Mu, Chia-Yu, Chen, Mei-Ling, Yan, Bo-Shiun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894228/
https://ncbi.nlm.nih.gov/pubmed/29642903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-018-0434-4
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