DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis

BACKGROUND: C-X-C motif ligand 8 (CXCL8), known as a proinflammatory chemokine, exerts multiple effects on the proliferation, invasion, and migration of tumor cells via the autocrine or paracrine manner. Conversely, the human Dachshund homologue 1 (DACH1) is recognized as a tumor suppressor which re...

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Bibliografiske detaljer
Udgivet i:J Hematol Oncol
Main Authors: Liu, Qian, Li, Anping, Yu, Shengnan, Qin, Shuang, Han, Na, Pestell, Richard G., Han, Xinwei, Wu, Kongming
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894143/
https://ncbi.nlm.nih.gov/pubmed/29636079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0597-1
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