Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology

Previous studies demonstrated that selenium in the form of sodium selenate reduces neurofibrillary tangle formation in Alzheimer’s disease models. Hyperphosphorylation of tau, which leads to formation of neurofibrillary tangles in Alzheimer’s disease, is increased by endoplasmic reticulum (ER) stres...

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Detaylı Bibliyografya
Yayımlandı:J Alzheimers Dis
Asıl Yazarlar: Rueli, Rachel H.L.H., Torres, Daniel J., Dewing, Andrea S.T., Kiyohara, Arlene C., Barayuga, Stephanie M., Bellinger, Miyoko T., Uyehara-Lock, Jane H., White, Lon R., Moreira, Paula I., Berry, Marla J., Perry, George, Bellinger, Frederick P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893862/
https://ncbi.nlm.nih.gov/pubmed/27802219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-151208
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