Overactivity of Alternative Pathway Convertases in Patients With Complement-Mediated Renal Diseases

Overactivation of the alternative pathway of the complement system is associated with the renal diseases atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G). C3 nephritic factors (C3NeF) play an important role in C3G pathogenesis by stabilizing the key enzymatic complex of compleme...

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發表在:Front Immunol
Main Authors: Michels, Marloes A. H. M., van de Kar, Nicole C. A. J., Okrój, Marcin, Blom, Anna M., van Kraaij, Sanne A. W., Volokhina, Elena B., van den Heuvel, Lambertus P. W. J.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893837/
https://ncbi.nlm.nih.gov/pubmed/29670616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00612
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