Regulation of Human γδ T Cells by BTN3A1 Protein Stability and ATP-Binding Cassette Transporters

Activation of human Vγ9/Vδ2 T cells by “phosphoantigens” (pAg), the microbial metabolite (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMB-PP) and the endogenous isoprenoid intermediate isopentenyl pyrophosphate, requires expression of butyrophilin BTN3A molecules by presenting cells. However, th...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Rhodes, David A., Chen, Hung-Chang, Williamson, James C., Hill, Alfred, Yuan, Jack, Smith, Sam, Rhodes, Harriet, Trowsdale, John, Lehner, Paul J., Herrmann, Thomas, Eberl, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893821/
https://ncbi.nlm.nih.gov/pubmed/29670629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00662
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