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Targeting Tumor-Associated Macrophages as a Potential Strategy to Enhance the Response to Immune Checkpoint Inhibitors

Inhibition of immune checkpoint pathways in CD8(+) T cell is a promising therapeutic strategy for the treatment of solid tumors that has shown significant anti-tumor effects and is now approved by the FDA to treat patients with melanoma and lung cancer. However the response to this therapy is limite...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Cassetta, Luca, Kitamura, Takanori
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893801/
https://ncbi.nlm.nih.gov/pubmed/29670880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00038
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