The Prenylflavonoid Xanthohumol Reduces Alzheimer-Like Changes and Modulates Multiple Pathogenic Molecular Pathways in the Neuro2a/APP(swe) Cell Model of AD

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that has proved refractory to drug treatment. Given evidence of neuroprotection in animal models of ischemic stroke, we assessed the prenylflavonoid xanthohumol from the Common Hop (Humulus lupulus L.) for therapeutic potential in...

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書目詳細資料
發表在:Front Pharmacol
Main Authors: Huang, Xianfeng, Wang, Jing, Chen, Xiao, Liu, Pan, Wang, Shujin, Song, Fangchen, Zhang, Zaijun, Zhu, Feiqi, Huang, Xinfeng, Liu, Jianjun, Song, Guoqiang, Spencer, Peter S., Yang, Xifei
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
主題:
Pharmacology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893754/
https://ncbi.nlm.nih.gov/pubmed/29670521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00199
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