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Dopamine induces soluble α-synuclein oligomers and nigrostriatal degeneration
Parkinson’s disease is defined by the loss of dopaminergic neurons in the substantia nigra and formation of Lewy body inclusions containing aggregated α-synuclein. Efforts to explain dopamine neuron vulnerability are hindered by the lack of dopaminergic cell death in α-synuclein transgenic mice. To...
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| Pubblicato in: | Nat Neurosci |
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| Autori principali: | , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5893155/ https://ncbi.nlm.nih.gov/pubmed/28920936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4641 |
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