Nephron segment-specific gene expression using AAV vectors

AAV9 vector provides efficient gene transfer in all segments of the renal nephron, with minimum expression in non-renal cells, when administered retrogradely via the ureter. It is important to restrict the transgene expression to the desired cell type within the kidney, so that the physiological end...

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Bibliographic Details
Published in:Biochem Biophys Res Commun
Main Authors: Asico, Laureano D., Cuevas, Santiago, Ma, Xiaobo, Jose, Pedro A., Armando, Ines, Konkalmatt, Prasad R.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893140/
https://ncbi.nlm.nih.gov/pubmed/29407172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.01.169
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