Experimental evolution of diverse Escherichia coli metabolic mutants identifies genetic loci for convergent adaptation of growth rate

Cell growth is determined by substrate availability and the cell’s metabolic capacity to assimilate substrates into building blocks. Metabolic genes that determine growth rate may interact synergistically or antagonistically, and can accelerate or slow growth, depending on genetic background and env...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Wytock, Thomas P., Fiebig, Aretha, Willett, Jonathan W., Herrou, Julien, Fergin, Aleksandra, Motter, Adilson E., Crosson, Sean
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892946/
https://ncbi.nlm.nih.gov/pubmed/29584733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007284
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