The role of the C-domain of bacteriophage T4 gene 32 protein in ssDNA binding and dsDNA helix-destabilization: Kinetic, single-molecule, and cross-linking studies

The model single-stranded DNA binding protein of bacteriophage T4, gene 32 protein (gp32) has well-established roles in DNA replication, recombination, and repair. gp32 is a single-chain polypeptide consisting of three domains. Based on thermodynamics and kinetics measurements, we have proposed that...

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Udgivet i:PLoS One
Main Authors: Pant, Kiran, Anderson, Brian, Perdana, Hendrik, Malinowski, Matthew A., Win, Aye T., Pabst, Christopher, Williams, Mark C., Karpel, Richard L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892887/
https://ncbi.nlm.nih.gov/pubmed/29634784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194357
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