Incorporating Cystatin C to Predict Methotrexate Elimination in Patients with CNS Lymphoma and Suspicious Renal Function

High-dose methotrexate (MTX; ≥1 g/m(2)) is a renally eliminated and nephrotoxic first-line therapy for central nervous system (CNS) lymphoma. Creatinine-based estimation of renal function is the recommended approach to dosing MTX in these cases, but nonrenal determinants of creatinine production and...

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Detalhes bibliográficos
Publicado no:Case Rep Hematol
Main Authors: Barreto, Jason N., McClanahan, Allison L., Rule, Andrew D., Thompson, Carrie A., Frazee, Erin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892267/
https://ncbi.nlm.nih.gov/pubmed/29780646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7169897
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