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Principles and methods of in-silico prioritization of non-coding regulatory variants

Over a decade of genome-wide association studies have made great strides toward the detection of genes and genetic mechanisms underlying complex traits. However, the majority of associated loci reside in non-coding regions that are functionally uncharacterized in general. Now, the availability of la...

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Bibliographic Details
Published in:Hum Genet
Main Authors: Lee, Phil, Lee, Christian, Li, Xihao, Wee, Brian, Dwivedi, Tushar, Daly, Mark
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892192/
https://ncbi.nlm.nih.gov/pubmed/29288389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-017-1861-0
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