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A general method for the metal-free, regioselective, remote C–H halogenation of 8-substituted quinolines

An operationally simple and metal-free protocol for geometrically inaccessible C5–H halogenation of a range of 8-substituted quinoline derivatives has been established. The reaction proceeds under air, with inexpensive and atom economical trihaloisocyanuric acid as a halogen source (only 0.36 equiv....

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書目詳細資料
發表在:Chem Sci
Main Authors: Motati, Damoder Reddy, Uredi, Dilipkumar, Watkins, E. Blake
格式: Artigo
語言:Inglês
出版: Royal Society of Chemistry 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892134/
https://ncbi.nlm.nih.gov/pubmed/29675222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc04107a
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