A Single Amino Acid Change in the Response Regulator PhoP, Acquired during Yersinia pestis Evolution, Affects PhoP Target Gene Transcription and Polymyxin B Susceptibility

Yersinia pestis, the causative agent of plague, evolved from the closely related pathogen Yersinia pseudotuberculosis. During its emergence, Y. pestis is believed to have acquired its unique pathogenic characteristics through numerous gene gains/losses, genomic rearrangements, and single nucleotide...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Fukuto, Hana S., Vadyvaloo, Viveka, McPhee, Joseph B., Poinar, Hendrik N., Holmes, Edward C., Bliska, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892123/
https://ncbi.nlm.nih.gov/pubmed/29440252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00050-18
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