Investigation into the role of the germline epigenome in the transmission of glucocorticoid-programmed effects across generations

BACKGROUND: Early life exposure to adverse environments affects cardiovascular and metabolic systems in the offspring. These programmed effects are transmissible to a second generation through both male and female lines, suggesting germline transmission. We have previously shown that prenatal overex...

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Detalles Bibliográficos
Publicado en:Genome Biol
Main Authors: Cartier, Jessy, Smith, Thomas, Thomson, John P., Rose, Catherine M., Khulan, Batbayar, Heger, Andreas, Meehan, Richard R., Drake, Amanda J.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891941/
https://ncbi.nlm.nih.gov/pubmed/29636086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1422-4
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