Dysregulation of Δ(4)-3-oxosteroid 5β-reductase in Diabetic Patients: Implications and Mechanisms

Aldo-keto reductase family 1 member D1 (AKR1D1) is a Δ(4)-3-oxosteroid 5β-reductase required for bile acid synthesis and steroid hormone metabolism. Both bile acids and steroid hormones, especially glucocorticoids, play important roles in regulating body metabolism and energy expenditure. Currently,...

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Vydáno v:Mol Cell Endocrinol
Hlavní autoři: Valanejad, Leila, Ghareeb, Mwlod, Shiffka, Stephanie, Nadolny, Christina, Chen, Yuan, Guo, Liangran, Verma, Ruchi, You, Sangmin, Akhlaghi, Fatemeh, Deng, Ruitang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891389/
https://ncbi.nlm.nih.gov/pubmed/29024782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2017.10.005
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