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Tunicamycin inhibits cell proliferation and migration in hepatocellular carcinoma through suppression of CD44s and the ERK1/2 pathway

Tunicamycin (TM) is an N‐linked glycosylation (NLG) inhibitor with strong antitumor activity, the exact underlying molecular mechanism of which remains to be elucidated. In our previous studies, we found that TM reversed drug resistance and improved the efficacy of combination treatments for hepatoc...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Hou, Helei, Ge, Chao, Sun, Hefen, Li, Hong, Li, Jinjun, Tian, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891198/
https://ncbi.nlm.nih.gov/pubmed/29377347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13518
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