Tumor evolution and drug response in patient-derived organoid models of bladder cancer

Bladder cancer is the fifth most prevalent cancer in the U.S., yet is understudied and few laboratory models exist that reflect the biology of the human disease. Here we describe a biobank of patient-derived organoid lines that recapitulates the histopathological and molecular diversity of human bla...

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Vydáno v:Cell
Hlavní autoři: Lee, Suk Hyung, Hu, Wenhuo, Matulay, Justin T., Silva, Mark V., Owczarek, Tomasz B., Kim, Kwanghee, Chua, Chee Wai, Barlow, LaMont J., Kandoth, Cyriac, Williams, Alanna B., Bergren, Sarah K., Pietzak, Eugene J., Anderson, Christopher B., Benson, Mitchell C., Coleman, Jonathan A., Taylor, Barry S., Abate-Shen, Cory, McKiernan, James M., Al-Ahmadie, Hikmat, Solit, David B., Shen, Michael M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890941/
https://ncbi.nlm.nih.gov/pubmed/29625057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.03.017
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