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Regulation of mRNA stability by CCCH-type zinc-finger proteins in immune cells

Current studies using knockout mice have revealed that some Cys–Cys–Cys–His (CCCH)-type zinc-finger proteins, namely tristetraprolin (TTP), Roquin and Regnase-1, play important roles in the immune system. These proteins are closely associated with the fate of their target RNAs in normal immune respo...

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Bibliographic Details
Published in:Int Immunol
Main Authors: Maeda, Kazuhiko, Akira, Shizuo
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890888/
https://ncbi.nlm.nih.gov/pubmed/28369485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxx015
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