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Safety, tolerability and pharmacokinetics of subcutaneous and intravenous anifrolumab in healthy volunteers
OBJECTIVES: To compare the pharmacokinetics (PK), safety and tolerability of subcutaneous (SC) and intravenous anifrolumab, an anti–type I interferon receptor monoclonal antibody in development for SLE, in healthy volunteers. METHODS: In this Phase I randomised, placebo-controlled study, 30 adults w...
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| Publicado en: | Lupus Sci Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMJ Publishing Group
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5890854/ https://ncbi.nlm.nih.gov/pubmed/29644080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2017-000252 |
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