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Revisiting the mutant prevention concentration to guide dosing in childhood tuberculosis

The mutant prevention concentration (MPC) is a well-known concept in the chemotherapy of many bacterial infections, but is seldom considered in relation to tuberculosis (TB) treatment, as the required concentrations are generally viewed as unachievable without undue toxicity. Early studies revealed...

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Dades bibliogràfiques
Publicat a:J Antimicrob Chemother
Autors principals: Jaganath, Devan, Schaaf, H. Simon, Donald, Peter R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890770/
https://ncbi.nlm.nih.gov/pubmed/28333284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx051
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