VT-1161 protects mice against oropharyngeal candidiasis caused by fluconazole-susceptible and -resistant Candida albicans

BACKGROUND: Candida albicans, the most common human fungal pathogen, causes chronic mucosal infections in patients with inborn errors of IL-17 immunity that rely heavily on chronic, often lifelong, azole antifungal agents for treatment. However, a rise in azole resistance has predicated a need for d...

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Vydáno v:J Antimicrob Chemother
Hlavní autoři: Break, Timothy J, Desai, Jigar V, Natarajan, Mukil, Ferre, Elise M N, Henderson, Christina, Zelazny, Adrian M, Siebenlist, Ulrich, Hoekstra, William J, Schotzinger, Robert J, Garvey, Edward P, Lionakis, Michail S
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890729/
https://ncbi.nlm.nih.gov/pubmed/29040636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx352
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