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Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance

OBJECTIVES: To investigate the performance of the two backbone drugs in the standard combination therapy regimen in the hollow-fibre system (HFS) model of pulmonary Mycobacterium avium complex (MAC) infection. METHODS: Six HFS were inoculated with human-derived monocytes infected with MAC, and treat...

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Veröffentlicht in:J Antimicrob Chemother
Hauptverfasser: Srivastava, Shashikant, Deshpande, Devyani, Gumbo, Tawanda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890692/
https://ncbi.nlm.nih.gov/pubmed/28922805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx303
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