Pretreatment HIV drug resistance results in virological failure and accumulation of additional resistance mutations in Ugandan children

BACKGROUND: Pretreatment HIV drug resistance (PDR) can impair virological response to ART, jeopardizing effective treatment for children. METHODS: Children aged ≤12 years initiated first-line ART in Uganda during 2010–11. Baseline and 6 monthly viral load (VL) and genotypic resistance testing if VL ...

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Vydáno v:J Antimicrob Chemother
Hlavní autoři: Kityo, Cissy, Boerma, Ragna S., Sigaloff, Kim C. E., Kaudha, Elizabeth, Calis, Job C. J., Musiime, Victor, Balinda, Sheila, Nakanjako, Rita, Boender, T. Sonia, Mugyenyi, Peter N., Rinke de Wit, Tobias F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890670/
https://ncbi.nlm.nih.gov/pubmed/28673027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx188
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