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Investigation of the solvent-dependent photolysis of a nonnucleoside reverse-transcriptase inhibitor, antiviral agent efavirenz

This study sought to investigate the solvent-dependency on the photolysis of efavirenz to gain insight into the photoprocesses involved. The primary mechanisms were firstly the excited-state intramolecular proton transfer (i.e. phototautomerization), which generated the imidic acid phototautomer obs...

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Publicat a:Antivir Chem Chemother
Autors principals: Jordaan, Maryam A, Shapi, Michael
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890511/
https://ncbi.nlm.nih.gov/pubmed/28893089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040206617730170
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