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Nigral Stress-Induced Dopamine Release in Clinical High Risk and Antipsychotic-Naïve Schizophrenia

BACKGROUND: Striatal dopamine (DA) synthesis capacity and release are elevated in schizophrenia (SCZ) and its putative prodrome, the clinical high risk (CHR) state. Striatal DA function results from the activity of midbrain DA neurons projecting mainly from the substantia nigra (SN). Elevated stress...

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Bibliografiske detaljer
Udgivet i:Schizophr Bull
Main Authors: Tseng, Huai-Hsuan, Watts, Jeremy J, Kiang, Michael, Suridjan, Ivonne, Wilson, Alan A, Houle, Sylvain, Rusjan, Pablo M, Mizrahi, Romina
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890468/
https://ncbi.nlm.nih.gov/pubmed/29036383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx042
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