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Overexpression of Truncated Human DISC1 Induces Appearance of Hindbrain Oligodendroglia in the Forebrain During Development

Genetic, neuroimaging, and gene expression studies suggest a role for oligodendrocyte (OLG) dysfunction in schizophrenia (SZ). Disrupted-in-schizophrenia 1 (DISC1) is a risk gene for major psychiatric disorders, including SZ. Overexpression of mutant truncated (hDISC1), but not full-length sequence...

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Bibliografske podrobnosti
izdano v:Schizophr Bull
Main Authors: Katsel, Pavel, Fam, Peter, Tan, Weilun, Khan, Sonia, Yang, Chunxia, Jouroukhin, Yan, Rudchenko, Sergei, Pletnikov, Mikhail V, Haroutunian, Vahram
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890457/
https://ncbi.nlm.nih.gov/pubmed/28981898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx106
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