Arginase Inhibition Suppresses Native Low-Density Lipoprotein-Stimulated Vascular Smooth Muscle Cell Proliferation by NADPH Oxidase Inactivation

PURPOSE: Vascular smooth muscle cell (VSMC) proliferation induced by native low-density lipoprotein (nLDL) stimulation is dependent on superoxide production from activated NADPH oxidase. The present study aimed to investigate whether the novel arginase inhibitor limonin could suppress nLDL-induced V...

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Veröffentlicht in:Yonsei Med J
Hauptverfasser: Koo, Bon-Hyeock, Yi, Bong-Gu, Wang, Wi-Kwang, Ko, In-Young, Hoe, Kwang-Lae, Kwon, Young-Guen, Won, Moo-Ho, Kim, Young-Myeong, Lim, Hyun Kyo, Ryoo, Sungwoo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Yonsei University College of Medicine 2018
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889988/
https://ncbi.nlm.nih.gov/pubmed/29611398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2018.59.3.366
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