Potential of Real-time PCR threshold cycle (C(T)) to predict presence of free toxin and clinically relevant C. difficile infection (CDI) in patients with cancer

OBJECTIVES: Clostridium difficile infection (CDI) is a toxin-mediated disease. Oncology patients are at increased risk for developing CDI. Diagnosis of CDI by PCR has led to misclassification of some C. difficile carriers as CDI cases. We determined if an optimized C. difficile PCR cycle threshold v...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Infect
Prif Awduron: Kamboj, Mini, Brite, Jennifer, McMillen, Tracy, Robilotti, Elizabeth, Herrera, Alejandro, Sepkowitz, Kent, Babady, N. Esther
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889955/
https://ncbi.nlm.nih.gov/pubmed/29229281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinf.2017.12.001
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