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Potential of Real-time PCR threshold cycle (C(T)) to predict presence of free toxin and clinically relevant C. difficile infection (CDI) in patients with cancer

OBJECTIVES: Clostridium difficile infection (CDI) is a toxin-mediated disease. Oncology patients are at increased risk for developing CDI. Diagnosis of CDI by PCR has led to misclassification of some C. difficile carriers as CDI cases. We determined if an optimized C. difficile PCR cycle threshold v...

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Dettagli Bibliografici
Pubblicato in:J Infect
Autori principali: Kamboj, Mini, Brite, Jennifer, McMillen, Tracy, Robilotti, Elizabeth, Herrera, Alejandro, Sepkowitz, Kent, Babady, N. Esther
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889955/
https://ncbi.nlm.nih.gov/pubmed/29229281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinf.2017.12.001
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