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Dendrite Growth and the Effect of Ectopic Rheb Expression on Cortical Neurons
Ras homology enriched in brain (Rheb) is a GTPase that activates the protein kinase mammalian Target of Rapamycin (mTOR). Rheb mutations cause intellectual delay and megalencephaly. mTOR hyperactivation causes a constellation of neurodevelopmental disorders called “mTOR-opathies” that are frequently...
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| Pubblicato in: | Neurosci Lett |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5889745/ https://ncbi.nlm.nih.gov/pubmed/29447953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2018.02.021 |
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