Haemophilus influenzae genome evolution during persistence in the human airways in chronic obstructive pulmonary disease

Nontypeable Haemophilus influenzae (NTHi) exclusively colonize and infect humans and are critical to the pathogenesis of chronic obstructive pulmonary disease (COPD). In vitro and animal models do not accurately capture the complex environments encountered by NTHi during human infection. We conducte...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Pettigrew, Melinda M., Ahearn, Christian P., Gent, Janneane F., Kong, Yong, Gallo, Mary C., Munro, James B., D’Mello, Adonis, Sethi, Sanjay, Tettelin, Hervé, Murphy, Timothy F.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889651/
https://ncbi.nlm.nih.gov/pubmed/29555745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719654115
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