Haemophilus influenzae genome evolution during persistence in the human airways in chronic obstructive pulmonary disease

Nontypeable Haemophilus influenzae (NTHi) exclusively colonize and infect humans and are critical to the pathogenesis of chronic obstructive pulmonary disease (COPD). In vitro and animal models do not accurately capture the complex environments encountered by NTHi during human infection. We conducte...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Pettigrew, Melinda M., Ahearn, Christian P., Gent, Janneane F., Kong, Yong, Gallo, Mary C., Munro, James B., D’Mello, Adonis, Sethi, Sanjay, Tettelin, Hervé, Murphy, Timothy F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2018
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889651/
https://ncbi.nlm.nih.gov/pubmed/29555745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719654115
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