Haemophilus influenzae genome evolution during persistence in the human airways in chronic obstructive pulmonary disease

Nontypeable Haemophilus influenzae (NTHi) exclusively colonize and infect humans and are critical to the pathogenesis of chronic obstructive pulmonary disease (COPD). In vitro and animal models do not accurately capture the complex environments encountered by NTHi during human infection. We conducte...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pettigrew, Melinda M., Ahearn, Christian P., Gent, Janneane F., Kong, Yong, Gallo, Mary C., Munro, James B., D’Mello, Adonis, Sethi, Sanjay, Tettelin, Hervé, Murphy, Timothy F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889651/
https://ncbi.nlm.nih.gov/pubmed/29555745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719654115
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