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Division-independent differentiation mandates proliferative competition among stem cells

Cancer-initiating gatekeeper mutations that arise in stem cells would be especially potent if they stabilize and expand an affected stem cell lineage. It is therefore important to understand how different stem cell organization strategies promote or prevent variant stem cell amplification in respons...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Reilein, Amy, Melamed, David, Tavaré, Simon, Kalderon, Daniel
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889645/
https://ncbi.nlm.nih.gov/pubmed/29555768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718646115
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