Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes

BACKGROUND: Genetic variants within the fatty acid desaturase (FADS) gene cluster (human Chr11) are important regulators of long-chain (LC) polyunsaturated fatty acid (PUFA) biosynthesis in the liver and consequently have been associated with circulating LC-PUFA levels. More recently, epigenetic mod...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Rahbar, Elaheh, Waits, Charlotte Mae K., Kirby, Edward H., Miller, Leslie R., Ainsworth, Hannah C., Cui, Tao, Sergeant, Susan, Howard, Timothy D., Langefeld, Carl D., Chilton, Floyd H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889567/
https://ncbi.nlm.nih.gov/pubmed/29636834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0480-5
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