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Pharmacological inhibition of IL-6 trans-signaling improves compromised fracture healing after severe trauma

Patients with multiple injuries frequently suffer bone fractures and are at high risk to develop fracture healing complications. Because of its key role both in systemic posttraumatic inflammation and fracture healing, the pleiotropic cytokine interleukin-6 (IL-6) may be involved in the pathomechani...

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Bibliografske podrobnosti
izdano v:Naunyn Schmiedebergs Arch Pharmacol
Main Authors: Kaiser, Kathrin, Prystaz, Katja, Vikman, Anna, Haffner-Luntzer, Melanie, Bergdolt, Stephanie, Strauss, Gudrun, Waetzig, Georg H., Rose-John, Stefan, Ignatius, Anita
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889421/
https://ncbi.nlm.nih.gov/pubmed/29497762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-018-1483-7
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