Enhanced protection of C57 BL/6 vs Balb/c mice to melanoma liver metastasis is mediated by NK cells

The B16F10 murine melanoma cell line displays a low expression of MHC class I molecules favoring immune evasion and metastases in immunocompetent C57 BL/6 wild-type mice. Here, we generated metastases to the liver, an organ that is skewed towards immune tolerance, by intrasplenic injection of B16F10...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Foerster, Friedrich, Boegel, Sebastian, Heck, Rosario, Pickert, Geetha, Rüssel, Nina, Rosigkeit, Sebastian, Bros, Matthias, Strobl, Stephanie, Kaps, Leonard, Aslam, Misbah, Diken, Mustafa, Castle, John, Sahin, Ugur, Tuettenberg, Andrea, Bockamp, Ernesto, Schuppan, Detlef
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889278/
https://ncbi.nlm.nih.gov/pubmed/29632723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1409929
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