Safety and activity of PD-1 blockade-activated DC-CIK cells in patients with advanced solid tumors

Cytokine-induced killer (CIK) cells that are stimulated using mature dendritic cells (DCs), referred to as (DC-CIK cells) exhibit superior anti-tumor potency. Anti-programmed death-1 (PD-1) antibodies reinvigorate T cell-mediated antitumor immunity. This phase I study aimed to assess the safety and...

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Gepubliceerd in:Oncoimmunology
Hoofdauteurs: Chen, Chang-Long, Pan, Qiu-Zhong, Weng, De-Sheng, Xie, Chuan-Miao, Zhao, Jing-Jing, Chen, Min-Shan, Peng, Rui-Qing, Li, Dan-Dan, Wang, Ying, Tang, Yan, Wang, Qi-Jing, Zhang, Zhi-Ling, Zhang, Xiao-Fei, Jiang, Li-Juan, Zhou, Zi-Qi, Zhu, Qian, He, Jia, Liu, Yuan, Zhou, Fang-Jian, Xia, Jian-Chuan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2018
Onderwerpen:
Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889206/
https://ncbi.nlm.nih.gov/pubmed/29632736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1417721
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