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Differentially Expressed mRNA Targets of Differentially Expressed miRNAs Predict Changes in the TP53 Axis and Carcinogenesis-Related Pathways in Human Keratinocytes Chronically Exposed to Arsenic

Arsenic is a widely distributed toxic natural element. Chronic arsenic ingestion causes several cancers, especially skin cancer. Arsenic-induced cancer mechanisms are not well defined, but several studies indicate that mutation is not the driving force and that microRNA expression changes play a rol...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Al-Eryani, Laila, Waigel, Sabine, Tyagi, Ashish, Peremarti, Jana, Jenkins, Samantha F, Damodaran, Chendil, States, J C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889014/
https://ncbi.nlm.nih.gov/pubmed/29319823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx292
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