The importance of small polar radiometabolites in molecular neuroimaging: A PET study with [(11)C]Cimbi-36 labeled in two positions

[(11)C]Cimbi-36, a 5-HT(2A) receptor agonist PET radioligand, contains three methoxy groups amenable to [(11)C]-labeling. In pigs, [(11)C]Cimbi-36 yields a polar (M1) and a less polar (M2) radiometabolite fraction, while changing the labeling to [(11)C]Cimbi-36_5 yields only the M1 fraction. We inve...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Johansen, Annette, Hansen, Hanne D, Svarer, Claus, Lehel, Szabolcs, Leth-Petersen, Sebastian, Kristensen, Jesper L, Gillings, Nic, Knudsen, Gitte M
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888860/
https://ncbi.nlm.nih.gov/pubmed/29215308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17746179
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados