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F234. TYPICAL AND ATYPICAL ANTIPSYCHOTICS’ D2R AFFINITY AND DOSES INFLUENCES POSTSYNAPTIC DENSITY BY MODULATING THE SPATIAL EXPRESSION OF HOMER1A A GENE HIGHLY IMPLICATED IN SYNAPTIC PLASTICITY AND PSYCHOSIS

BACKGROUND: Post-synaptic density (PSD) is an ultra-specialized structure of excitatory synapses composed by a large variety of molecules (scaffolding proteins, glutamate receptors, cytoskeleton proteins). PSD has been implicated in synaptic plasticity, memory formation and in the pathophysiology of...

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Dettagli Bibliografici
Pubblicato in:Schizophr Bull
Autori principali: Camilla, Avagliano, Buonaguro, Elisabetta, Tomasetti, Carmine, Marmo, Federica, Vellucci, Licia, Iasevoli, Felice, de Bartolomeis, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888784/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sby017.765
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