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F41. SCHIZOPHRENIA-RELEVANT ALTERATIONS IN CEREBRAL METABOLISM, GLUTAMATE AND MONOAMINERGIC NEUROTRANSMITTER SYSTEM FUNCTION IN A MOUSE MODEL OF 16P11.2 DUPLICATION

BACKGROUND: Duplication at 16p11.2, affecting approximately 30 genes, has consistently been associated with increased risk of schizophrenia (Psychiatric Genomics Consortium, 2017. Nat Genet 49: 27). We currently have little understanding of how this CNV impacts on brain and neurotransmitter system f...

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Bibliografske podrobnosti
izdano v:Schizophr Bull
Main Authors: Bristow, Greg, Thomson, David, Pratt, Judith, Morris, Brian, Dawson, Neil
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888678/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sby017.572
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