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F232. A PHASE 3 STUDY TO DETERMINE THE ANTIPSYCHOTIC EFFICACY AND SAFETY OF ALKS 3831 IN ADULT PATIENTS WITH ACUTE EXACERBATION OF SCHIZOPHRENIA

BACKGROUND: ALKS 3831, currently under development for the treatment of schizophrenia, is composed of a flexible dose of olanzapine (OLZ) and a fixed dose of 10 mg of samidorphan. In a Phase 2 study, ALKS 3831 mitigated OLZ-associated weight gain and exhibited antipsychotic efficacy similar to OLZ a...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: McDonnell, David, Potkin, Steven G, Simmons, Adam, Jiang, Ying, DiPetrillo, Lauren, Silverman, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888656/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sby017.763
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